Intermethod Differences in Results for Total PSA, Free PSA, and Percentage of Free PSA
نویسندگان
چکیده
منابع مشابه
Population-based analysis of normal Total PSA and percentage of free/Total PSA values: results from screening cohort.
OBJECTIVES To examine the distribution of total prostate-specific antigen (tPSA) and percentage of free/total PSA (%f/tPSA) values in patients undergoing prostate cancer screening in Canada. METHODS The data from 4 consecutive annual prostate cancer screening events held in Montreal, Canada were examined with respect to age, tPSA, and %f/tPSA in 3222 men. RESULTS Within the entire cohort, t...
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assays for prostate cancer screening, Afssaps has conducted, in the context of its mission, a market survey of devices indicating quantitative results. The objective of this survey was to evaluate the analytical performances of these assays, particularly to verify the accuracy of total PSA, free PSA and complexed PSA assay kits and to study the equimolarity of total PSA reagents in the analogou...
متن کاملCorrelation between the complex PSA/total PSA ratio and the free PSA/total PSA ratio, sensitivity and specificity of both markers for the diagnosis of prostate cancer.
OBJECTIVE To compare the behaviour of the PSAcomplex/PSAtotal percentage (PSAc%) against the PSA free/PSA total (PSAl%) and analyse both markers for their usefulness in diagnosing prostate cancer. MATERIAL AND METHODS We measured total PSA (PSAt), free PSA (PSAl), complex PSA (PSAc), PSAl% and PSAc% levels in 158 patients. Of these, 98 (62%) were biopsied for presenting PSAt≥3 ng/dl and PSAl%...
متن کاملThe significance of TPSA, free to total PSA ratio and PSA density in prostate carcinoma diagnostics.
Prostate-specific antigen (PSA) is the one of the most valuable tumor markers for the early detection and management of prostate carcinoma, but not an ideal one because of poor specificity in the case of prostatic hypertrophy and other benign conditions. In order to overcome this drawback some other parameters as is free to total ratio (F/T) PSA and PSA density (PSAD) are introduced. It has bee...
متن کاملComparison of prostate-specific antigen (PSA) measured by four combinations of free PSA and total PSA assays.
We compared prostate-specific antigen (PSA) assay systems [i.e., free PSA (f-PSA) and the corresponding total PSA (t-PSA) assay] from four different manufacturers as well as the f-PSA/t-PSA ratios with regard to their ability to discriminate between benign prostate hyperplasia (BPH) and prostate cancer (PCA). ROC analysis showed similar areas under the curves (AUCs) with different assay systems...
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ژورنال
عنوان ژورنال: American Journal of Clinical Pathology
سال: 2008
ISSN: 0002-9173,1943-7722
DOI: 10.1309/jybpmfnuf6eyy9tb